Osmitrol (Mannitol)
Know the triple O’s with Osmitrol

Osmitrol is an osmotic diuretic. It focuses on increasing the osmotic pressure of the glomerular filtrate. Osmitrol, osmotic diuretic, and osmotic pressure all start with the letter O.

The higher the concentration of osmitrol in the filtrate, the more diuresis occurs (more fluid removal).

Uses of Osmitrol
Know what Osmitrol is used for.

What is Osmitrol (Mannitol) used for:

  • Prevents, treats oliguric phase (also starts with the letter O) of acute renal failure.
  • Reduces increased intracranial pressure caused by cerebral edema.
  • Decreases edema of injured spinal cord.
  • Decreases intraocular pressure caused by acute glaucoma.
  • Promotes excretion of toxic substances.
When Not to Use Osmitrol
Know when not to use Osmitrol and know which patients to be cautious in using Osmitrol with.

Do not use Osmitrol (Mannitol) for:

  • Severe renal disease
  • Dehydration
  • Intracranial bleeding
  • Severe pulmonary edema

Be cautious in using Osmitrol (Mannitol) when patient has:

  • Cardiac failure
  • Pulmonary edema
Side Effects of Osmitrol
It is essential to know the side effects of Osmitrol.

Side effects of Osmitrol (Mannitol):

  • Blurred vision
  • Dizziness
  • Tachycardia
  • Peripheral edema
  • Headache
  • Nausea and vomiting (of course)
  • Backache
Nursing Actions of Osmitrol
Know the nursing actions you need to take when administering Osmitrol to a patient.

Nursing actions to take:

  • Check vital signs before administering the dose (Got to look at that blood pressure).
  • Assess urinary output and hydration status
  • Assess electrolytes (for low sodium and potassium).
  • Assess BUN, renal, and hepatic panels.
  • Look for symptoms of congestive heart failure and pulmonary edema.
  • IV medication may crystallize so it is essential to warm prior to putting into solution to prevent from entering circulation.

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