Potassium can send you down into a spiral. That is why Spironolactone (Aldactone) is a potassium-sparing diuretic!

Spironolactone (Aldactone) has a direct effect on the distal tubules in the kidney. It gets into a fight with aldosterone for cell receptors sites while inducing urinary excretion of sodium and reducing excretion of potassium and hydrogen ions.

This is important when you want to avoid getting rid of too much potassium in the body.

Know what Spironolactone is used for

Spironolactone (Aldactone) is used to:

  • Treat hypertension and edema.
  • Reduce edema in clients with severe heart failure.
When Not to Use Spironolactone
Know when not to administer Spironolactone

Do not use Spironolactone (Aldactone) for patients with:

  • Hypersensitivity (of course think about allergies)
  • Renal failure
  • Anuria
  • Hyperkalemia (if the medication does not get rid of potassium, then why give it to a patient with an overload of potassium?)

 Be cautious in administering this medication to patients with renal dysfunction.

Side Effects of Spironolactone
Know the side effects of Spironolactone

Side effects to watch out for:

  • Hyperkalemia
  • Hyponatremia
  • Weakness
  • Dehydration
  • Hyperglycemia
  • Hirsuitism
  • Menstrual irregularities
  • Gynecomastia
  • Impotence
  • Deepening of voice
Nursing Actions of Spironolactone
Know the nursing implications of Spironolactone

Nursing actions to take with Spironolactone (Aldactone) administration:

  • Monitor intake and output.
  • Watch for cardiac dysrhythmias.
  • Monitor levels of electrolytes (too much potassium, too little sodium).
  • Tell patients to report cramps, weakness, fatigue, nausea, or any of the above side effects mentioned.

Page 1 – Top Key Points You Need to Know About Diuretics

Page 2 – What You Need to Know About Osmitrol for the NCLEX